{"id":931,"date":"2026-01-02T13:05:55","date_gmt":"2026-01-02T13:05:55","guid":{"rendered":"https:\/\/bihelab.di.ionio.gr\/?page_id=931"},"modified":"2026-01-17T18:21:45","modified_gmt":"2026-01-17T16:21:45","slug":"projects-2","status":"publish","type":"page","link":"https:\/\/bihelab.di.ionio.gr\/index.php\/projects-2\/","title":{"rendered":"Research Projects"},"content":{"rendered":"<p>[et_pb_section fb_built=&#8221;1&#8243; disabled_on=&#8221;on|on|on&#8221; _builder_version=&#8221;4.27.4&#8243; _module_preset=&#8221;default&#8221; background_image=&#8221;http:\/\/bihelab.di.ionio.gr\/wp-content\/uploads\/2026\/01\/Picture1.jpg&#8221; background_size=&#8221;custom&#8221; background_image_width=&#8221;43%&#8221; background_image_height=&#8221;0%&#8221; background_position=&#8221;top_right&#8221; background_vertical_offset=&#8221;23%&#8221; background_enable_mask_style=&#8221;on&#8221; background_mask_style=&#8221;diagonal&#8221; background_mask_aspect_ratio=&#8221;portrait&#8221; background_mask_size=&#8221;cover&#8221; background_mask_position=&#8221;center_right&#8221; background_mask_horizontal_offset=&#8221;-72%&#8221; custom_padding=&#8221;||112px|||&#8221; disabled=&#8221;on&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_row _builder_version=&#8221;4.27.4&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_column type=&#8221;4_4&#8243; _builder_version=&#8221;4.27.4&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_heading title=&#8221;Projects&#8221; title_tablet=&#8221;Projects&#8221; title_phone=&#8221;Projects&#8221; title_last_edited=&#8221;on|desktop&#8221; _builder_version=&#8221;4.27.4&#8243; _module_preset=&#8221;default&#8221; title_font_size=&#8221;49px&#8221; global_colors_info=&#8221;{}&#8221;][\/et_pb_heading][et_pb_text _builder_version=&#8221;4.27.4&#8243; _module_preset=&#8221;default&#8221; custom_margin=&#8221;|456px||||&#8221; global_colors_info=&#8221;{}&#8221;][\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=&#8221;1&#8243; fullwidth=&#8221;on&#8221; _builder_version=&#8221;4.27.4&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_fullwidth_header title=&#8221;Research Projects&#8221; subhead=&#8221;Projects our laboratory has led &#8221; text_orientation=&#8221;center&#8221; _builder_version=&#8221;4.27.4&#8243; _module_preset=&#8221;default&#8221; subhead_text_align=&#8221;center&#8221; subhead_font_size=&#8221;22px&#8221; background_image=&#8221;http:\/\/bihelab.di.ionio.gr\/wp-content\/uploads\/2026\/01\/lab_blured.jpg&#8221; custom_margin=&#8221;||||false|false&#8221; custom_padding=&#8221;150px||150px||true|false&#8221; global_colors_info=&#8221;{}&#8221;][\/et_pb_fullwidth_header][\/et_pb_section][et_pb_section fb_built=&#8221;1&#8243; theme_builder_area=&#8221;post_content&#8221; _builder_version=&#8221;4.27.4&#8243; _module_preset=&#8221;default&#8221;][et_pb_row _builder_version=&#8221;4.27.4&#8243; _module_preset=&#8221;default&#8221; theme_builder_area=&#8221;post_content&#8221;][et_pb_column _builder_version=&#8221;4.27.4&#8243; _module_preset=&#8221;default&#8221; type=&#8221;4_4&#8243; theme_builder_area=&#8221;post_content&#8221;][et_pb_code _builder_version=&#8221;4.27.4&#8243; _module_preset=&#8221;default&#8221; theme_builder_area=&#8221;post_content&#8221; hover_enabled=&#8221;0&#8243; sticky_enabled=&#8221;0&#8243;]<!-- BiHELab Research Projects - Divi Compatible --><!-- [et_pb_line_break_holder] --><!-- [et_pb_line_break_holder] --><\/p>\n<style><!-- [et_pb_line_break_holder] -->.bihelab-projects-container {<!-- [et_pb_line_break_holder] -->  max-width: 1080px;<!-- [et_pb_line_break_holder] -->  margin: 0 auto;<!-- [et_pb_line_break_holder] -->  padding: 40px 20px;<!-- [et_pb_line_break_holder] -->}<!-- [et_pb_line_break_holder] --><!-- [et_pb_line_break_holder] -->.bihelab-projects-container h2 {<!-- [et_pb_line_break_holder] -->  font-family: 'Open Sans', -apple-system, BlinkMacSystemFont, sans-serif;<!-- [et_pb_line_break_holder] -->  font-size: 26px;<!-- [et_pb_line_break_holder] -->  font-weight: 600;<!-- [et_pb_line_break_holder] -->  color: #1a1a1a;<!-- [et_pb_line_break_holder] -->  margin: 0 0 30px 0;<!-- [et_pb_line_break_holder] -->}<!-- [et_pb_line_break_holder] --><!-- [et_pb_line_break_holder] -->.bihelab-project-item {<!-- [et_pb_line_break_holder] -->  padding: 28px 0;<!-- [et_pb_line_break_holder] -->  border-bottom: 1px solid #eaeaea;<!-- [et_pb_line_break_holder] -->}<!-- [et_pb_line_break_holder] --><!-- [et_pb_line_break_holder] -->.bihelab-project-item:first-child {<!-- [et_pb_line_break_holder] -->  padding-top: 0;<!-- [et_pb_line_break_holder] -->}<!-- [et_pb_line_break_holder] --><!-- [et_pb_line_break_holder] -->.bihelab-project-item h3 {<!-- [et_pb_line_break_holder] -->  font-family: 'Open Sans', -apple-system, BlinkMacSystemFont, sans-serif;<!-- [et_pb_line_break_holder] -->  font-size: 18px;<!-- [et_pb_line_break_holder] -->  font-weight: 600;<!-- [et_pb_line_break_holder] -->  color: #1a1a1a;<!-- [et_pb_line_break_holder] -->  margin: 0 0 10px 0;<!-- [et_pb_line_break_holder] -->}<!-- [et_pb_line_break_holder] --><!-- [et_pb_line_break_holder] -->.bihelab-project-item p {<!-- [et_pb_line_break_holder] -->  font-family: 'Open Sans', -apple-system, BlinkMacSystemFont, sans-serif;<!-- [et_pb_line_break_holder] -->  font-size: 15px;<!-- [et_pb_line_break_holder] -->  line-height: 1.7;<!-- [et_pb_line_break_holder] -->  color: #555;<!-- [et_pb_line_break_holder] -->  margin: 0 0 14px 0;<!-- [et_pb_line_break_holder] -->}<!-- [et_pb_line_break_holder] --><!-- [et_pb_line_break_holder] -->.bihelab-project-item a.project-link {<!-- [et_pb_line_break_holder] -->  font-family: 'Open Sans', -apple-system, BlinkMacSystemFont, sans-serif;<!-- [et_pb_line_break_holder] -->  font-size: 14px;<!-- [et_pb_line_break_holder] -->  font-weight: 500;<!-- [et_pb_line_break_holder] -->  color: #2271b1;<!-- [et_pb_line_break_holder] -->  text-decoration: none;<!-- [et_pb_line_break_holder] -->  display: inline-flex;<!-- [et_pb_line_break_holder] -->  align-items: center;<!-- [et_pb_line_break_holder] -->  gap: 6px;<!-- [et_pb_line_break_holder] -->  transition: color 0.2s ease;<!-- [et_pb_line_break_holder] -->}<!-- [et_pb_line_break_holder] --><!-- [et_pb_line_break_holder] -->.bihelab-project-item a.project-link:hover {<!-- [et_pb_line_break_holder] -->  color: #135e96;<!-- [et_pb_line_break_holder] -->}<!-- [et_pb_line_break_holder] --><!-- [et_pb_line_break_holder] -->.bihelab-project-item a.project-link svg {<!-- [et_pb_line_break_holder] -->  width: 14px;<!-- [et_pb_line_break_holder] -->  height: 14px;<!-- [et_pb_line_break_holder] -->  transition: transform 0.2s ease;<!-- [et_pb_line_break_holder] -->}<!-- [et_pb_line_break_holder] --><!-- [et_pb_line_break_holder] -->.bihelab-project-item a.project-link:hover svg {<!-- [et_pb_line_break_holder] -->  transform: translateX(3px);<!-- [et_pb_line_break_holder] -->}<!-- [et_pb_line_break_holder] --><\/style>\n<p><!-- [et_pb_line_break_holder] --><!-- [et_pb_line_break_holder] --><\/p>\n<div class=\"bihelab-projects-container\"><!-- [et_pb_line_break_holder] -->  <\/p>\n<h2>Research Projects<\/h2>\n<p><!-- [et_pb_line_break_holder] -->  <!-- [et_pb_line_break_holder] -->  <\/p>\n<div class=\"bihelab-project-item\"><!-- [et_pb_line_break_holder] -->    <\/p>\n<h3>Neurosystem<\/h3>\n<p><!-- [et_pb_line_break_holder] -->    <pee>Design and development of a decision support system for the collection and analysis of multidimensional data from patients with neurodegenerative diseases. The project includes studying factors that influence disease progression, drafting collection and analysis protocols, developing an information system, and integrating data mining techniques.<\/pee><!-- [et_pb_line_break_holder] -->    <a class=\"project-link\" href=\"https:\/\/bihelab.di.ionio.gr\/projects\/nevrosystima\/\" target=\"_blank\" rel=\"noopener\">View project <svg xmlns=\"http:\/\/www.w3.org\/2000\/svg\" fill=\"none\" viewBox=\"0 0 24 24\" stroke=\"currentColor\" stroke-width=\"2\"><path stroke-linecap=\"round\" stroke-linejoin=\"round\" d=\"M17 8l4 4m0 0l-4 4m4-4H3\" \/><\/svg><\/a><!-- [et_pb_line_break_holder] -->  <\/div>\n<p><!-- [et_pb_line_break_holder] --><!-- [et_pb_line_break_holder] -->  <\/p>\n<div class=\"bihelab-project-item\"><!-- [et_pb_line_break_holder] -->    <\/p>\n<h3>Neuroprogression<\/h3>\n<p><!-- [et_pb_line_break_holder] -->    <pee>Research focused on the development of computational tools for assessing the progression of non-genetic neurodegenerative diseases using biomarkers. The project involves the collection and recording of clinical data, analysis of correlations between biomarkers, phenotypes, and disease stages, as well as the development of computational software for personalized evaluation of disease progression.<\/pee><!-- [et_pb_line_break_holder] -->    <a class=\"project-link\" href=\"https:\/\/bihelab.di.ionio.gr\/projects\/nevroexelixi\/\" target=\"_blank\" rel=\"noopener\">View project <svg xmlns=\"http:\/\/www.w3.org\/2000\/svg\" fill=\"none\" viewBox=\"0 0 24 24\" stroke=\"currentColor\" stroke-width=\"2\"><path stroke-linecap=\"round\" stroke-linejoin=\"round\" d=\"M17 8l4 4m0 0l-4 4m4-4H3\" \/><\/svg><\/a><!-- [et_pb_line_break_holder] -->  <\/div>\n<p><!-- [et_pb_line_break_holder] --><!-- [et_pb_line_break_holder] -->  <\/p>\n<div class=\"bihelab-project-item\"><!-- [et_pb_line_break_holder] -->    <\/p>\n<h3>Neuroeducation<\/h3>\n<p><!-- [et_pb_line_break_holder] -->    <pee>Enhancement of cognitive abilities in individuals with Mild Cognitive Impairment through a measurable behavioral study. Using electrophysiological data from brain activity recordings, targeted interventions are designed, and tools are developed to support memory improvement, strengthen cognitive skills, and restore cognitive deficits.<\/pee><!-- [et_pb_line_break_holder] -->    <a class=\"project-link\" href=\"https:\/\/bihelab.di.ionio.gr\/projects\/%ce%bd%ce%b5%cf%85%cf%81%ce%bf%ce%b5%ce%ba%cf%80%ce%b1%ce%af%ce%b4%ce%b5%cf%85%cf%83%ce%b7\/\" target=\"_blank\" rel=\"noopener\">View project <svg xmlns=\"http:\/\/www.w3.org\/2000\/svg\" fill=\"none\" viewBox=\"0 0 24 24\" stroke=\"currentColor\" stroke-width=\"2\"><path stroke-linecap=\"round\" stroke-linejoin=\"round\" d=\"M17 8l4 4m0 0l-4 4m4-4H3\" \/><\/svg><\/a><!-- [et_pb_line_break_holder] -->  <\/div>\n<p><!-- [et_pb_line_break_holder] --><!-- [et_pb_line_break_holder] -->  <\/p>\n<div class=\"bihelab-project-item\"><!-- [et_pb_line_break_holder] -->    <\/p>\n<h3>Neurotrial<\/h3>\n<p><!-- [et_pb_line_break_holder] -->    <pee>Study of clinical trial protocols incorporating computational biomarkers for non-genetic neurodegenerative diseases. The goal is to investigate the feasibility and potential benefits of using these biomarkers, identify the most relevant and informative markers for different disease types, and evaluate their ability to monitor disease progression and predict treatment outcomes.<\/pee><!-- [et_pb_line_break_holder] -->    <a class=\"project-link\" href=\"https:\/\/bihelab.di.ionio.gr\/projects\/nevrodokimi\/\" target=\"_blank\" rel=\"noopener\">View project <svg xmlns=\"http:\/\/www.w3.org\/2000\/svg\" fill=\"none\" viewBox=\"0 0 24 24\" stroke=\"currentColor\" stroke-width=\"2\"><path stroke-linecap=\"round\" stroke-linejoin=\"round\" d=\"M17 8l4 4m0 0l-4 4m4-4H3\" \/><\/svg><\/a><!-- [et_pb_line_break_holder] -->  <\/div>\n<p><!-- [et_pb_line_break_holder] --><!-- [et_pb_line_break_holder] -->  <\/p>\n<div class=\"bihelab-project-item\"><!-- [et_pb_line_break_holder] -->    <\/p>\n<h3>Neuropharma<\/h3>\n<p><!-- [et_pb_line_break_holder] -->    <pee>Study of pharmacological protocols for the treatment of non-genetic neurodegenerative diseases using computational biomarkers. The aim is to identify the most effective therapies and evaluate how computational biomarkers can be used to monitor disease progression, predict treatment outcomes, and assess patient response.<\/pee><!-- [et_pb_line_break_holder] -->    <a class=\"project-link\" href=\"https:\/\/bihelab.di.ionio.gr\/projects\/nevrofarma\/\" target=\"_blank\" rel=\"noopener\">View project <svg xmlns=\"http:\/\/www.w3.org\/2000\/svg\" fill=\"none\" viewBox=\"0 0 24 24\" stroke=\"currentColor\" stroke-width=\"2\"><path stroke-linecap=\"round\" stroke-linejoin=\"round\" d=\"M17 8l4 4m0 0l-4 4m4-4H3\" \/><\/svg><\/a><!-- [et_pb_line_break_holder] -->  <\/div>\n<p><!-- [et_pb_line_break_holder] --><!-- [et_pb_line_break_holder] -->  <\/p>\n<div class=\"bihelab-project-item\"><!-- [et_pb_line_break_holder] -->    <\/p>\n<h3>FOLDIT<\/h3>\n<p><!-- [et_pb_line_break_holder] -->    <pee>Development of Research Infrastructure at the Ionian University for the Study of Protein Folding in Neurodegenerative Diseases. The project aims to detect and study the folding and aggregation of selected protein motifs involved in relevant pathological mechanisms, combining specialized experimental techniques, such as atomic force microscopy, with modern computational approaches. Special emphasis is placed on the morphology, spatial distribution, and temporal evolution of protein aggregates, as well as on determining the minimum time required for their reliable imaging.<\/pee><!-- [et_pb_line_break_holder] -->    <a class=\"project-link\" href=\"https:\/\/bihelab.di.ionio.gr\/projects\/foldit\/\" target=\"_blank\" rel=\"noopener\">View project <svg xmlns=\"http:\/\/www.w3.org\/2000\/svg\" fill=\"none\" viewBox=\"0 0 24 24\" stroke=\"currentColor\" stroke-width=\"2\"><path stroke-linecap=\"round\" stroke-linejoin=\"round\" d=\"M17 8l4 4m0 0l-4 4m4-4H3\" \/><\/svg><\/a><!-- [et_pb_line_break_holder] -->  <\/div>\n<p><!-- [et_pb_line_break_holder] --><!-- [et_pb_line_break_holder] -->  <\/p>\n<div class=\"bihelab-project-item\"><!-- [et_pb_line_break_holder] -->    <\/p>\n<h3>BIODIANEA<\/h3>\n<p><!-- [et_pb_line_break_holder] -->    <pee>The project aims to carry out industrial research and development of a biochip, with a particular focus on its application for the diagnosis and treatment of neurodegenerative diseases, especially Parkinson&#8217;s disease. The biochips will be integrated with data processing and decision support systems to establish a comprehensive platform for disease risk assessment and diagnosis. Experimental and pilot activities will be conducted to ensure the highest level of operational readiness.<\/pee><!-- [et_pb_line_break_holder] -->    <a class=\"project-link\" href=\"http:\/\/biodianea.gr\/\" target=\"_blank\" rel=\"noopener\">View project <svg xmlns=\"http:\/\/www.w3.org\/2000\/svg\" fill=\"none\" viewBox=\"0 0 24 24\" stroke=\"currentColor\" stroke-width=\"2\"><path stroke-linecap=\"round\" stroke-linejoin=\"round\" d=\"M17 8l4 4m0 0l-4 4m4-4H3\" \/><\/svg><\/a><!-- [et_pb_line_break_holder] -->  <\/div>\n<p><!-- [et_pb_line_break_holder] --><!-- [et_pb_line_break_holder] -->  <\/p>\n<div class=\"bihelab-project-item\"><!-- [et_pb_line_break_holder] -->    <\/p>\n<h3>National Research Network for Uncovering the Genetic Basis of Alzheimer&#8217;s and Parkinson&#8217;s Diseases, Detecting Reliable Biomarkers, and Developing Innovative Computational Technologies and Therapeutic Strategies Based on Precision Medicine<\/h3>\n<p><!-- [et_pb_line_break_holder] -->    <pee>The project aims to study Alzheimer&#8217;s and Parkinson&#8217;s neurodegenerative diseases. It involves patient registration and the creation of biological sample biobank, biochemical and molecular characterization of samples, development of cellular and animal models, computational tools for early diagnosis, and the design of innovative preclinical therapeutic interventions.<\/pee><!-- [et_pb_line_break_holder] -->    <a class=\"project-link\" href=\"https:\/\/brainprecision.gr\/index.php\/el\/\" target=\"_blank\" rel=\"noopener\">View project <svg xmlns=\"http:\/\/www.w3.org\/2000\/svg\" fill=\"none\" viewBox=\"0 0 24 24\" stroke=\"currentColor\" stroke-width=\"2\"><path stroke-linecap=\"round\" stroke-linejoin=\"round\" d=\"M17 8l4 4m0 0l-4 4m4-4H3\" \/><\/svg><\/a><!-- [et_pb_line_break_holder] -->  <\/div>\n<p><!-- [et_pb_line_break_holder] --><!-- [et_pb_line_break_holder] --><\/div>\n<p>[\/et_pb_code][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=&#8221;1&#8243; specialty=&#8221;on&#8221; _builder_version=&#8221;4.27.4&#8243; _module_preset=&#8221;default&#8221; custom_margin=&#8221;-5px|||||&#8221; hover_enabled=&#8221;0&#8243; global_colors_info=&#8221;{}&#8221; disabled_on=&#8221;on|on|on&#8221; disabled=&#8221;on&#8221; sticky_enabled=&#8221;0&#8243;][et_pb_column type=&#8221;1_2&#8243; specialty_columns=&#8221;2&#8243; _builder_version=&#8221;4.16&#8243; custom_padding=&#8221;|||&#8221; global_colors_info=&#8221;{}&#8221; custom_padding__hover=&#8221;|||&#8221;][et_pb_row_inner _builder_version=&#8221;4.27.4&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_column_inner saved_specialty_column_type=&#8221;1_2&#8243; _builder_version=&#8221;4.27.4&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_heading title=&#8221;Neurosystem&#8221; _builder_version=&#8221;4.27.4&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221;][\/et_pb_heading][et_pb_text _builder_version=&#8221;4.27.4&#8243; _module_preset=&#8221;default&#8221; text_font_size=&#8221;19px&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<p style=\"font-weight: 400;\">Design and development of a decision support system for the collection and analysis of multidimensional data from patients with neurodegenerative diseases. The project includes studying factors that influence disease progression, drafting collection and analysis protocols, developing an information system, and integrating data mining techniques<\/p>\n<p>[\/et_pb_text][et_pb_button button_url=&#8221;https:\/\/bihelab.di.ionio.gr\/projects\/nevrosystima\/&#8221; url_new_window=&#8221;on&#8221; button_text=&#8221;More&#8221; button_alignment=&#8221;right&#8221; _builder_version=&#8221;4.27.4&#8243; _module_preset=&#8221;default&#8221; custom_button=&#8221;on&#8221; button_text_color=&#8221;#0C71C3&#8243; button_border_width=&#8221;0px&#8221; button_on_hover=&#8221;off&#8221; global_colors_info=&#8221;{}&#8221;][\/et_pb_button][\/et_pb_column_inner][\/et_pb_row_inner][\/et_pb_column][et_pb_column type=&#8221;1_2&#8243; _builder_version=&#8221;4.16&#8243; custom_padding=&#8221;|||&#8221; global_colors_info=&#8221;{}&#8221; custom_padding__hover=&#8221;|||&#8221;][et_pb_image src=&#8221;http:\/\/bihelab.di.ionio.gr\/wp-content\/uploads\/2026\/01\/Screenshot-2026-01-02-123946.png&#8221; title_text=&#8221;Screenshot 2026-01-02 123946&#8243; _builder_version=&#8221;4.27.4&#8243; _module_preset=&#8221;default&#8221; min_height=&#8221;100px&#8221; height=&#8221;475px&#8221; max_height=&#8221;500px&#8221; custom_padding=&#8221;||0px|||&#8221; global_colors_info=&#8221;{}&#8221;][\/et_pb_image][\/et_pb_column][\/et_pb_section][et_pb_section fb_built=&#8221;1&#8243; specialty=&#8221;on&#8221; _builder_version=&#8221;4.27.4&#8243; _module_preset=&#8221;default&#8221; hover_enabled=&#8221;0&#8243; global_colors_info=&#8221;{}&#8221; disabled_on=&#8221;on|on|on&#8221; disabled=&#8221;on&#8221; sticky_enabled=&#8221;0&#8243;][et_pb_column type=&#8221;1_2&#8243; specialty_columns=&#8221;2&#8243; _builder_version=&#8221;4.16&#8243; custom_padding=&#8221;|||&#8221; global_colors_info=&#8221;{}&#8221; custom_padding__hover=&#8221;|||&#8221;][et_pb_row_inner _builder_version=&#8221;4.27.4&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_column_inner saved_specialty_column_type=&#8221;1_2&#8243; _builder_version=&#8221;4.27.4&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_image src=&#8221;http:\/\/bihelab.di.ionio.gr\/wp-content\/uploads\/2026\/01\/videoframe_10937-scaled.png&#8221; title_text=&#8221;videoframe_10937&#8243; _builder_version=&#8221;4.27.4&#8243; _module_preset=&#8221;default&#8221; min_height=&#8221;100px&#8221; height=&#8221;475px&#8221; max_height=&#8221;500px&#8221; custom_padding=&#8221;|0px|0px|||&#8221; global_colors_info=&#8221;{}&#8221;][\/et_pb_image][\/et_pb_column_inner][\/et_pb_row_inner][\/et_pb_column][et_pb_column type=&#8221;1_2&#8243; _builder_version=&#8221;4.16&#8243; custom_padding=&#8221;|||&#8221; global_colors_info=&#8221;{}&#8221; custom_padding__hover=&#8221;|||&#8221;][et_pb_heading title=&#8221;Neuroprogression&#8221; _builder_version=&#8221;4.27.4&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221;][\/et_pb_heading][et_pb_text _builder_version=&#8221;4.27.4&#8243; _module_preset=&#8221;default&#8221; text_font_size=&#8221;19px&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<p style=\"font-weight: 400; text-align: justify;\">Research focused on the development of computational tools for assessing the progression of non-genetic neurodegenerative diseases using biomarkers. The project involves the collection and recording of clinical data, analysis of correlations between biomarkers, phenotypes, and disease stages, as well as the development of computational software for personalized evaluation of disease progression.<\/p>\n<p style=\"text-align: justify;\"><span><\/span><\/p>\n<p>[\/et_pb_text][et_pb_button button_url=&#8221;https:\/\/bihelab.di.ionio.gr\/projects\/nevroexelixi\/&#8221; url_new_window=&#8221;on&#8221; button_text=&#8221;More&#8221; button_alignment=&#8221;right&#8221; _builder_version=&#8221;4.27.4&#8243; _module_preset=&#8221;default&#8221; custom_button=&#8221;on&#8221; button_text_color=&#8221;#0C71C3&#8243; button_border_width=&#8221;0px&#8221; button_on_hover=&#8221;off&#8221; global_colors_info=&#8221;{}&#8221;][\/et_pb_button][\/et_pb_column][\/et_pb_section][et_pb_section fb_built=&#8221;1&#8243; specialty=&#8221;on&#8221; _builder_version=&#8221;4.27.4&#8243; _module_preset=&#8221;default&#8221; hover_enabled=&#8221;0&#8243; global_colors_info=&#8221;{}&#8221; disabled_on=&#8221;on|on|on&#8221; disabled=&#8221;on&#8221; sticky_enabled=&#8221;0&#8243;][et_pb_column type=&#8221;1_2&#8243; specialty_columns=&#8221;2&#8243; _builder_version=&#8221;4.16&#8243; custom_padding=&#8221;|||&#8221; global_colors_info=&#8221;{}&#8221; custom_padding__hover=&#8221;|||&#8221;][et_pb_row_inner _builder_version=&#8221;4.27.4&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_column_inner saved_specialty_column_type=&#8221;1_2&#8243; _builder_version=&#8221;4.27.4&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_heading title=&#8221;Neuroeducation&#8221; _builder_version=&#8221;4.27.4&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221;][\/et_pb_heading][et_pb_text _builder_version=&#8221;4.27.4&#8243; _module_preset=&#8221;default&#8221; text_font_size=&#8221;19px&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<div class=\"wp-block-uagb-advanced-heading uagb-block-a5e306bf\">\n<p style=\"font-weight: 400;\">Enhancement of cognitive abilities in individuals with Mild Cognitive Impairment through a measurable behavioral study. Using electrophysiological data from brain activity recordings, targeted interventions are designed, and tools are developed to support memory improvement, strengthen cognitive skills, and restore cognitive deficits.<\/p>\n<\/div>\n<p>[\/et_pb_text][et_pb_button button_url=&#8221;https:\/\/bihelab.di.ionio.gr\/projects\/%ce%bd%ce%b5%cf%85%cf%81%ce%bf%ce%b5%ce%ba%cf%80%ce%b1%ce%af%ce%b4%ce%b5%cf%85%cf%83%ce%b7\/&#8221; url_new_window=&#8221;on&#8221; button_text=&#8221;More&#8221; button_alignment=&#8221;right&#8221; _builder_version=&#8221;4.27.4&#8243; _module_preset=&#8221;default&#8221; custom_button=&#8221;on&#8221; button_text_color=&#8221;#0C71C3&#8243; button_border_width=&#8221;0px&#8221; button_on_hover=&#8221;off&#8221; global_colors_info=&#8221;{}&#8221;][\/et_pb_button][\/et_pb_column_inner][\/et_pb_row_inner][\/et_pb_column][et_pb_column type=&#8221;1_2&#8243; _builder_version=&#8221;4.16&#8243; custom_padding=&#8221;|||&#8221; global_colors_info=&#8221;{}&#8221; custom_padding__hover=&#8221;|||&#8221;][et_pb_image src=&#8221;http:\/\/bihelab.di.ionio.gr\/wp-content\/uploads\/2026\/01\/videoframe_13513.png&#8221; title_text=&#8221;videoframe_13513&#8243; _builder_version=&#8221;4.27.4&#8243; _module_preset=&#8221;default&#8221; width=&#8221;100%&#8221; min_height=&#8221;100px&#8221; height=&#8221;475px&#8221; max_height=&#8221;500px&#8221; custom_padding=&#8221;||0px|||&#8221; global_colors_info=&#8221;{}&#8221;][\/et_pb_image][\/et_pb_column][\/et_pb_section][et_pb_section fb_built=&#8221;1&#8243; specialty=&#8221;on&#8221; _builder_version=&#8221;4.27.4&#8243; _module_preset=&#8221;default&#8221; hover_enabled=&#8221;0&#8243; global_colors_info=&#8221;{}&#8221; disabled_on=&#8221;on|on|on&#8221; disabled=&#8221;on&#8221; sticky_enabled=&#8221;0&#8243;][et_pb_column type=&#8221;1_2&#8243; specialty_columns=&#8221;2&#8243; _builder_version=&#8221;4.16&#8243; custom_padding=&#8221;|||&#8221; global_colors_info=&#8221;{}&#8221; custom_padding__hover=&#8221;|||&#8221;][et_pb_row_inner _builder_version=&#8221;4.27.4&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_column_inner saved_specialty_column_type=&#8221;1_2&#8243; _builder_version=&#8221;4.27.4&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_image src=&#8221;http:\/\/bihelab.di.ionio.gr\/wp-content\/uploads\/2026\/01\/videoframe_1844.png&#8221; title_text=&#8221;videoframe_1844&#8243; _builder_version=&#8221;4.27.4&#8243; _module_preset=&#8221;default&#8221; min_height=&#8221;100px&#8221; height=&#8221;475px&#8221; max_height=&#8221;500px&#8221; custom_padding=&#8221;|0px|0px|||&#8221; global_colors_info=&#8221;{}&#8221;][\/et_pb_image][\/et_pb_column_inner][\/et_pb_row_inner][\/et_pb_column][et_pb_column type=&#8221;1_2&#8243; _builder_version=&#8221;4.16&#8243; custom_padding=&#8221;|||&#8221; global_colors_info=&#8221;{}&#8221; custom_padding__hover=&#8221;|||&#8221;][et_pb_heading title=&#8221;Neurotrial&#8221; _builder_version=&#8221;4.27.4&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221;][\/et_pb_heading][et_pb_text _builder_version=&#8221;4.27.4&#8243; _module_preset=&#8221;default&#8221; text_font_size=&#8221;19px&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<div class=\"wp-block-uagb-advanced-heading uagb-block-e5d944d5\">\n<p style=\"font-weight: 400; text-align: justify;\">Study of clinical trial protocols incorporating computational biomarkers for non-genetic neurodegenerative diseases. The goal is to investigate the feasibility and potential benefits of using these biomarkers, identify the most relevant and informative markers for different disease types, and evaluate their ability to monitor disease progression and predict treatment outcomes<\/p>\n<\/div>\n<p>[\/et_pb_text][et_pb_button button_url=&#8221;https:\/\/bihelab.di.ionio.gr\/projects\/nevrodokimi\/&#8221; url_new_window=&#8221;on&#8221; button_text=&#8221;More&#8221; button_alignment=&#8221;right&#8221; _builder_version=&#8221;4.27.4&#8243; _module_preset=&#8221;default&#8221; custom_button=&#8221;on&#8221; button_text_color=&#8221;#0C71C3&#8243; button_border_width=&#8221;0px&#8221; button_on_hover=&#8221;off&#8221; global_colors_info=&#8221;{}&#8221;][\/et_pb_button][\/et_pb_column][\/et_pb_section][et_pb_section fb_built=&#8221;1&#8243; specialty=&#8221;on&#8221; _builder_version=&#8221;4.27.4&#8243; _module_preset=&#8221;default&#8221; hover_enabled=&#8221;0&#8243; global_colors_info=&#8221;{}&#8221; disabled_on=&#8221;on|on|on&#8221; disabled=&#8221;on&#8221; sticky_enabled=&#8221;0&#8243;][et_pb_column type=&#8221;1_2&#8243; specialty_columns=&#8221;2&#8243; _builder_version=&#8221;4.16&#8243; custom_padding=&#8221;|||&#8221; global_colors_info=&#8221;{}&#8221; custom_padding__hover=&#8221;|||&#8221;][et_pb_row_inner _builder_version=&#8221;4.27.4&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_column_inner saved_specialty_column_type=&#8221;1_2&#8243; _builder_version=&#8221;4.27.4&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_heading title=&#8221;Neuropharma&#8221; _builder_version=&#8221;4.27.4&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221;][\/et_pb_heading][et_pb_text _builder_version=&#8221;4.27.4&#8243; _module_preset=&#8221;default&#8221; text_font_size=&#8221;19px&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<div class=\"wp-block-uagb-advanced-heading uagb-block-a5e306bf\">\n<div class=\"wp-block-uagb-advanced-heading uagb-block-f3334731\">\n<p style=\"font-weight: 400; text-align: justify;\">Study of pharmacological protocols for the treatment of non-genetic neurodegenerative diseases using computational biomarkers. The aim is to identify the most effective therapies and evaluate how computational biomarkers can be used to monitor disease progression, predict treatment outcomes, and assess patient response.<\/p>\n<\/div>\n<\/div>\n<p>[\/et_pb_text][et_pb_button button_url=&#8221;https:\/\/bihelab.di.ionio.gr\/projects\/nevrofarma\/&#8221; url_new_window=&#8221;on&#8221; button_text=&#8221;More&#8221; button_alignment=&#8221;right&#8221; _builder_version=&#8221;4.27.4&#8243; _module_preset=&#8221;default&#8221; custom_button=&#8221;on&#8221; button_text_color=&#8221;#0C71C3&#8243; button_border_width=&#8221;0px&#8221; button_on_hover=&#8221;off&#8221; global_colors_info=&#8221;{}&#8221;][\/et_pb_button][\/et_pb_column_inner][\/et_pb_row_inner][\/et_pb_column][et_pb_column type=&#8221;1_2&#8243; _builder_version=&#8221;4.16&#8243; custom_padding=&#8221;|||&#8221; global_colors_info=&#8221;{}&#8221; custom_padding__hover=&#8221;|||&#8221;][et_pb_image src=&#8221;http:\/\/bihelab.di.ionio.gr\/wp-content\/uploads\/2026\/01\/videoframe_6680.png&#8221; title_text=&#8221;videoframe_6680&#8243; _builder_version=&#8221;4.27.4&#8243; _module_preset=&#8221;default&#8221; width=&#8221;100%&#8221; min_height=&#8221;100px&#8221; height=&#8221;475px&#8221; max_height=&#8221;500px&#8221; custom_padding=&#8221;||0px|||&#8221; global_colors_info=&#8221;{}&#8221;][\/et_pb_image][\/et_pb_column][\/et_pb_section][et_pb_section fb_built=&#8221;1&#8243; specialty=&#8221;on&#8221; _builder_version=&#8221;4.27.4&#8243; _module_preset=&#8221;default&#8221; hover_enabled=&#8221;0&#8243; global_colors_info=&#8221;{}&#8221; disabled_on=&#8221;on|on|on&#8221; disabled=&#8221;on&#8221; sticky_enabled=&#8221;0&#8243;][et_pb_column type=&#8221;1_2&#8243; specialty_columns=&#8221;2&#8243; _builder_version=&#8221;4.16&#8243; custom_padding=&#8221;|||&#8221; global_colors_info=&#8221;{}&#8221; custom_padding__hover=&#8221;|||&#8221;][et_pb_row_inner _builder_version=&#8221;4.27.4&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_column_inner saved_specialty_column_type=&#8221;1_2&#8243; _builder_version=&#8221;4.27.4&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_image src=&#8221;http:\/\/bihelab.di.ionio.gr\/wp-content\/uploads\/2026\/01\/jpk-forcerobot-400-bruker.png&#8221; title_text=&#8221;jpk-forcerobot-400-bruker&#8221; _builder_version=&#8221;4.27.4&#8243; _module_preset=&#8221;default&#8221; min_height=&#8221;100px&#8221; height=&#8221;475px&#8221; max_height=&#8221;500px&#8221; custom_padding=&#8221;|0px|0px|||&#8221; global_colors_info=&#8221;{}&#8221;][\/et_pb_image][\/et_pb_column_inner][\/et_pb_row_inner][\/et_pb_column][et_pb_column type=&#8221;1_2&#8243; _builder_version=&#8221;4.16&#8243; custom_padding=&#8221;|||&#8221; global_colors_info=&#8221;{}&#8221; custom_padding__hover=&#8221;|||&#8221;][et_pb_heading title=&#8221;FOLDIT&#8221; _builder_version=&#8221;4.27.4&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221;][\/et_pb_heading][et_pb_text _builder_version=&#8221;4.27.4&#8243; _module_preset=&#8221;default&#8221; text_font_size=&#8221;19px&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<div class=\"wp-block-uagb-advanced-heading uagb-block-e5d944d5\">\n<div class=\"wp-block-uagb-advanced-heading uagb-block-780f437b\">\n<p style=\"font-weight: 400; text-align: justify;\">Development of Research Infrastructure at the Ionian University for the Study of Protein Folding in Neurodegenerative Diseases.<\/p>\n<p style=\"font-weight: 400; text-align: justify;\">The project aims to detect and study the folding and aggregation of selected protein motifs involved in relevant pathological mechanisms, combining specialized experimental techniques, such as atomic force microscopy, with modern computational approaches. Special emphasis is placed on the morphology, spatial distribution, and temporal evolution of protein aggregates, as well as on determining the minimum time required for their reliable imaging.<\/p>\n<\/div>\n<\/div>\n<p>[\/et_pb_text][et_pb_button button_url=&#8221;https:\/\/bihelab.di.ionio.gr\/projects\/foldit\/&#8221; url_new_window=&#8221;on&#8221; button_text=&#8221;More&#8221; button_alignment=&#8221;right&#8221; _builder_version=&#8221;4.27.4&#8243; _module_preset=&#8221;default&#8221; custom_button=&#8221;on&#8221; button_text_color=&#8221;#0C71C3&#8243; button_border_width=&#8221;0px&#8221; button_on_hover=&#8221;off&#8221; global_colors_info=&#8221;{}&#8221;][\/et_pb_button][\/et_pb_column][\/et_pb_section][et_pb_section fb_built=&#8221;1&#8243; specialty=&#8221;on&#8221; _builder_version=&#8221;4.27.4&#8243; _module_preset=&#8221;default&#8221; hover_enabled=&#8221;0&#8243; global_colors_info=&#8221;{}&#8221; disabled_on=&#8221;on|on|on&#8221; disabled=&#8221;on&#8221; sticky_enabled=&#8221;0&#8243;][et_pb_column type=&#8221;1_2&#8243; specialty_columns=&#8221;2&#8243; _builder_version=&#8221;4.16&#8243; custom_padding=&#8221;|||&#8221; global_colors_info=&#8221;{}&#8221; custom_padding__hover=&#8221;|||&#8221;][et_pb_row_inner _builder_version=&#8221;4.27.4&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_column_inner saved_specialty_column_type=&#8221;1_2&#8243; _builder_version=&#8221;4.27.4&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_heading title=&#8221;\u0392io-chips for the Diagnosis and Treatmnt of Neurodegenerative Diseases with a focus on Parkinson\u2019s Disease &#8211; \u0392\u0399\u039fDIANEA&#8221; _builder_version=&#8221;4.27.4&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221;][\/et_pb_heading][et_pb_text _builder_version=&#8221;4.27.4&#8243; _module_preset=&#8221;default&#8221; text_font_size=&#8221;19px&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<div class=\"wp-block-uagb-advanced-heading uagb-block-a5e306bf\">\n<div class=\"wp-block-uagb-advanced-heading uagb-block-f3334731\">\n<p style=\"font-weight: 400; text-align: justify;\">The project aims to carry out industrial research and development of a biochip, with a particular focus on its application for the diagnosis and treatment of neurodegenerative diseases, especially Parkinson\u2019s disease. The biochips will be integrated with data processing and decision support systems to establish a comprehensive platform for disease risk assessment and diagnosis. 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