Single Particle Optical Sizing

Single Particle Optical Sizing

The Accusizer 780 APS (ACCUSIZER – Single Particle Optical Sizing) can be used as a formulation development tool to determine temperature or time stability by monitoring the oversized particles in a dispersion undergoing change. The AccuSizer 780 reveals particle size differences that previously went unnoticed. The 780 is a stable, sensitive instrument that uses Single Particle Optical Sizing (SPOS) to count and size particles one at a time, eliminating missed particles while allowing:

  • Particle sensitivity of 10 PPT
  • Particle size accuracy of 2%
  • Particle count accuracy of 10%

The APS has been called the bolder detector by many of our customers because of its ability to detect low levels of aggregates several standard deviations away from the mean of the distribution. Often these aggregates are the difference between a good and bad sample. One independent study showed the APS was 1,500 to 25,000 times more sensitive in seeing outliers in the CMP slurry than commonly used laser light scattering and acoustical sizing instruments. The same sensitivity will apply to other applications such as inks, pigments, drug emulsions where a few large particles spell the difference between success and disaster.